Advances in research on in vivo-in vitro correlation of sustained-release oral dosage forms in traditional Chinese medicine.
- Author:
Li-Hua CHEN
1
;
De-Sheng XU
;
Yi FENG
Author Information
1. Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
- Publication Type:Journal Article
- MeSH:
Administration, Oral;
Delayed-Action Preparations;
Drugs, Chinese Herbal;
administration & dosage;
Medicine, Chinese Traditional;
methods
- From:
China Journal of Chinese Materia Medica
2008;33(3):333-338
- CountryChina
- Language:Chinese
-
Abstract:
In this review, methods for testing in vitro release rate of sustained release preparations of traditional Chinese medicine (TCM) and in vivo-in vitro correlation were introduced. Studies indicated that a good correlation between in vivo and in vitro release can be obtained by establishing methods of in vitro release and it is important for the development of sustained release drug delivery system in TCM.