Study on chemical constituents in rhizome of Securidaca inappendiculata.
- Author:
Lei SHI
1
;
Wen-Yi KANG
Author Information
- Publication Type:Journal Article
- MeSH: Antioxidants; analysis; pharmacology; Drugs, Chinese Herbal; chemistry; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Rhizome; chemistry; Securidaca; chemistry; Spectrometry, Mass, Electrospray Ionization
- From: China Journal of Chinese Materia Medica 2008;33(7):780-782
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Securidaca inappendiculata.
METHODColumn chromatographic techniques were applied to isolate constituents. A combination of MS and NMR spectroscopy was used to identify structures of constituents.
RESULTSeven compounds were isolated from the CHCl3 fraction and their structures were elucidated as 3, 4-dihydroxybezoic acid (1), 3-hydroxy-4-methoxylbenzoic acid (2), coniferaldehyde (3), 7-hydroxy-1, 2, 3, 8-tetrame thoxyxanthone (4), 1, 3, 8-trihydroxy-4-methoxyxanthone (5), 1, 3, 8-trihydroxy-2-methoxyxanth-one (6), 1, 3, 6-trihydroxy-2,7-dimethoxyxanthone (7).
CONCLUSIONCompounds 1-6 were isolated for the first time from the genus. The antioxidant activities of compounds 3-6 were assayed by the method of DPPH and compound 3 showed the IC50 value of 4.14 microg x mL(-1).
