Influence of Qingpeng plaster on blood vessels and mast cells in skin tissue of channel points of nude mice.
- Author:
Ming-Fu LUO
1
;
Cui-Hong LI
;
Dong ZHANG
;
Ying GUO
;
Jun-Na HE
;
Hui-Min MA
;
Shu-You WANG
;
Shun-Yue LI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Vessels; cytology; drug effects; Cell Count; Drugs, Chinese Herbal; administration & dosage; pharmacology; Female; Male; Mast Cells; cytology; drug effects; Mice; Mice, Nude; Skin; blood supply; cytology; drug effects
- From: China Journal of Chinese Materia Medica 2008;33(7):816-818
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the changes in the numbers of blood vessels and mast cells, which is relative to blood microcirculation in skin, during Qingpeng plaster (ZANG medicine) being applied to the skin surface of nude mice.
METHODFifteen healthy adult nude mice were divided into Qingpeng plaster group and the control group. The sites of skin tissues stuck with the plaster or with control plaster were selected after 7 days treated, and then all the slices stained and observed.
RESULTThe numbers of the vessels and the mast cells increased in the dermal tissue of Qingpeng paster group. Although there were a few dilated blood vessels in the control group, but the numbers of the vessels and the mast cells were obviously less than those of the Qingpeng plaster group. Statistical analysis showed that there was a significant difference (P < 0.001) between tow groups.
CONCLUSIONQingpeng plaster can cause obvious vascular dilatation and promot mast cells aggregation in the Qingpeng plaster stuck parts of the skin tissue.
