Comparison of computed tomography versus magnetic resonance imaging in assessing radiofrequency ablation margins after radiofrequency ablation in patients with hepatocellular carcinomas.
- Author:
Jin-rong QU
1
;
Cui-cui LIU
;
Hong-kai ZHANG
;
Xiang LI
;
Jian-wei ZHANG
;
Jun-peng LUO
;
Nan-nan SHAO
;
Shou-ning ZHANG
;
Yan-le LI
;
Hai-Liang LI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Carcinoma, Hepatocellular; diagnosis; pathology; surgery; Catheter Ablation; Female; Humans; Liver Neoplasms; diagnosis; pathology; surgery; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; diagnosis; Retrospective Studies; Sensitivity and Specificity; Tomography, X-Ray Computed
- From: Acta Academiae Medicinae Sinicae 2012;34(5):480-485
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo assess the diagnostic value of magnetic resonance imaging (MRI) in the follow-up of patients with hepatocellular carcinomas treated with radiofrequency ablation (RFA) and to compare it with that of computed tomography (CT).
METHODSFrom December 2009 to September 2011, 40 patients (47 hepatocellular carcinomas) were treated with RFA after transcatheter arterial chemoembolization and underwent MRI and CT for follow-up. RFA margins were assessed on a five-point scale with receiver operating characteristic curve analysis. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were evaluated.
RESULTSThe interobserver agreement rate for MRI was significantly higher (Kappa=0.935) than for CT (Kappa=0.714; P < 0.05). The scores of 1 and 5 points for MRI, which confirms the presence or absence of residual tumor, accounted for 89.4% (84/94), while for CT accounting for only 31.9% (30/94). The area under the receiver operating characteristic curve of MRI was significantly higher than that of CT (P < 0.05), as were the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of detection rate (mean, 100%, 96.4%, 76.9%, 100%, and 96.8% for MRI, respectively, vs. 30.0%, 57.1%, 10.3%, 87.7%, and 63.8% for CT).
CONCLUSIONMRI is superior to CT in assessing the RFA margins in terms of the diagnostic accuracy and detection rate .
