Hereditary antithrombin deficiency and hyperhomocysteinemia in venous thromboembolic disease.
10.3881/j.issn.1000-503X.2012.06.022
- Author:
Zheng XI-XI
1
;
Bing ZHONG-XING
;
Liu BAO
Author Information
1. Department of Vascular Surgery, PUMC Hospital, CAMS and PUMC, Beijing, China.
- Publication Type:Journal Article
- MeSH:
Antithrombin III Deficiency;
complications;
Humans;
Hyperhomocysteinemia;
complications;
Venous Thrombosis;
etiology
- From:
Acta Academiae Medicinae Sinicae
2012;34(6):645-648
- CountryChina
- Language:Chinese
-
Abstract:
Hypercoagulability state is the result of the interplay of genetic predisposition and risk factors. Many key enzymes and reactions in coagulation and anti-coagulation system are involved. Hereditary antithrombin deficiency is one of the major risk factors of venous thromboembolic disease (VTE), whereas hyperhomocysteinemia may also play a role. This article reviews the recent researches on the contributions of these two factors to VTE.
