Research update of Cullin protein in reproductive system.
- Author:
Ye TIAN
1
;
Han ZHAO
;
Zi-jiang CHEN
Author Information
1. Provincial Hospital Affiliated to Shandong University, Jinan, China.
- Publication Type:Journal Article
- MeSH:
Cullin Proteins;
Humans;
Urogenital System
- From:
Acta Academiae Medicinae Sinicae
2013;35(1):125-129
- CountryChina
- Language:Chinese
-
Abstract:
Culling protein is a member of Cullin-Ring-based E3-ligases ( CRLs family) , which belong to E3 ubiquitin ligases. Cullin plays diverse and essential roles in many biological processes through mediating the ubiquitination of target proteins. This article summarizes the potential functions of Culling proteins in gamete genesis and maturation, embryo development, and reproductive related disorders.
