Advancement in the research of early detection of bacterial nucleic acid in molecular diagnosis of sepsis.
- Author:
Xiao LIU
1
;
Hui REN
;
Dai-zhi PENG
Author Information
1. School of Nursing, the Third Military Medical University, Chongqing 400038, China.
- Publication Type:Journal Article
- MeSH:
DNA, Bacterial;
blood;
Humans;
Sepsis;
blood;
diagnosis
- From:
Chinese Journal of Burns
2013;29(2):166-172
- CountryChina
- Language:Chinese
-
Abstract:
Early diagnosis of sepsis helps make effective clinical decisions and improve the survival rate of patients with severe infection. However, the timely and accurate diagnosis of sepsis is still a great challenge in clinic. In order to settle the very problem, the scientists in the world have made a lot of exploration and research in the field of rapid molecular identification of pathogens. Nowadays, the nucleic acid detection of sepsis is mainly composed of 3 types of methodological strategies, either based on positive blood culture, single colonies, or directly on blood specimens. This paper presents a comprehensive overview of advances in the research of early detection of bacterial nucleic acid as molecular diagnosis of sepsis.