An epidemiological survey of acute lymphocytic leukemia from 2002 to 2006 in Shanghai..
- Author:
Xiong NI
1
;
Zhi-Xiang SHEN
;
Fang-Yuan CHEN
;
Hui LIANG
;
Jing-Yan TANG
;
Feng-Juan LU
;
Chun WANG
;
Jing-Bo SHAO
;
Jian HOU
;
Shan-Hua ZOU
;
Jian-Min WANG
Author Information
- Publication Type:Journal Article
- MeSH: China; Chromosome Aberrations; Humans; Immunophenotyping; Precursor Cell Lymphoblastic Leukemia-Lymphoma; genetics; Surveys and Questionnaires
- From: Chinese Journal of Hematology 2010;31(1):21-24
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyse the epidemiological data of acute lymphoblastic leukemia (ALL) in Shanghai.
METHODSALL cases in Shanghai from 2002 to 2006 were retrospectively investigated.
RESULTSAll together there were 544 newly diagnozed ALL cases. The yearly incidence of ALL was 0.81/10(5), which was slightly higher in men (0.86/10(5)) than in women (0.75/10(5)). The age-stratified incidence showed 2.31/10(5) in patients (pts) 60 y. The incidences in Chongming County was 0.60/10(5), being the lowest in all districts. The morphological types of ALL was L(1) (26.2%), L(2) (57.4%) and L(3) (16.4%); the immunophenotype was B (80.1%) and T (19.5%). The incidence of ALL with myeloid antigen expression was 20.2%. Genetic examination revealed that chromosome aberration of t(9;22) was the most common one.
CONCLUSIONSThe incidence of ALL in Shanghai is 0.81/10(5). Compared with the national standard (1986 - 1998), the incidence in adolescents is obviously increased. Chongming County has the lowest incidence, indicating a role of environment factor in ALL incidence.
