Purification technology of Rhizoma et Radix Notopterygii and Radix Angelicae Pubescentis in Fufang Xuelian dropping pills by macroporous resin.
- Author:
Yu-Qin LUO
1
;
Wei-Jun YANG
;
Jian-Guo XU
;
Jian-Guo XING
Author Information
- Publication Type:Journal Article
- MeSH: Angelica; chemistry; Apiaceae; chemistry; Drugs, Chinese Herbal; chemistry; isolation & purification; Plants, Medicinal; chemistry; Porosity; Resins, Synthetic; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(21):2478-2481
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the purification technology of Rhizoma et Radix Notopterygii and Radix Angelicae Pubescentis in Fufang Xuelian dropping pills by macroporous resin.
METHODTaking osthole, isomperatorin as index ingredients, the type of resin sampling amount and elution solvent were decided, and the influence of sample concentration pH of sample and ratio of diameter to height of column to adsorption were studied.
RESULTHPD400A was chosen to purify, the suitable sampling ratio of resin volume to raw material was 1:2; pH 3.5 (crude drug) and ratio of diameter to height was 1:7; 95% ethanol of the elution solvent was satisfactory eluant for desorption.
CONCLUSIONHPD400A macroporous resin can be used to purify Rhizoma et Radix Notopterygii and Radix Angelicae Pubescentis.
