Studies on chemical constituents of Illicium simonsii.
- Author:
Xiao-Ya SHANG
1
;
Miao-Ru GUO
;
Cong-Wei ZHAO
;
Shuai LI
Author Information
- Publication Type:Journal Article
- MeSH: Catechin; chemistry; Drugs, Chinese Herbal; chemistry; Ethanol; chemistry; Glycosides; chemistry; Illicium; chemistry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Rhamnose; analogs & derivatives; chemistry; Sitosterols; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(21):2490-2492
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents from the active fractions against HIV in vitro, a crude ethanolic extract of Illicium simonsii.
METHODThe compounds were isolated with column chromatography methods. MS and NMR spectroscopic methods were used to determine the structures of the compounds.
RESULTSeven compounds were isolated from the active fractions against HIV in vitro of the 90% ethanol extract and their structures were elucidated as (+)-catechin (1), (-)-epicatechin (2), (+)-catechin 3-O-alpha-L-rhamnopyranoside (3), kaempferol 3-O-alpha-L-rhamnopyranoside (4), quercetin 3-O-alpha-L-rhamnopyranoside (5), erigeside C (6) and daucosterol (7).
CONCLUSIONSeven compounds were isolated from this plant for the first time, but none of them exhibited active against HIV in vitro. Compounds 3 and 6 were isolated from this genus for the first time.
