Clinical analysis of hepatic veno-occlusive disease induced by Sedum aizoon.

Author: Guo-Lin WU ¹ ; Guo-You YU ; Jiu CHEN
Author Information

1. The first Affiliated Hospital College of Medicine, Zhejiang University, Hangzhou 310003, China. wuguolin28@yahoo.com.cn
Publication Type:Journal Article
MeSH: Adult; Aged; Drugs, Chinese Herbal; adverse effects; Female; Hepatic Veno-Occlusive Disease; chemically induced; pathology; Humans; Male; Middle Aged; Sedum; chemistry
From: China Journal of Chinese Materia Medica 2008;33(20):2402-2404
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo discuss the clinical characteristics and precautionary measures of hepatic veno-occlusive disease (VOD) caused by Sedum aizoon.
METHODThe VOD induced by Sedum aizoon were reports in 41 patients comimg from national medical journals from 1998 to 2007 and their use and dose were analyzed.
RESULTThe results shows that ADR of Sedum aizoon was serious. VOD has relationship with it, s dose use time the age of the patients and individual difference.
CONCLUSIONTo avoid of VOD induced by Sedum aizoon, it should be done through strengthening study on pharmacology and toxicology of Sedum aizoon. Enhancing patients of safety awareness, standardizing usage and dosage to guide the clinically rational use of drugs.