Study on biligustilides from Angelica sinensis.
- Author:
Xin-Hua LU
1
;
Jin-Juan ZHANG
;
Xue-Xia ZHANG
;
Hong LIANG
;
Yu-Ying ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: Angelica sinensis; chemistry; Benzofurans; chemistry; Drugs, Chinese Herbal; chemistry; Molecular Structure
- From: China Journal of Chinese Materia Medica 2008;33(19):2196-2201
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Angelica sinensis.
METHODThe constituents were separated by chromatographic methods, and their structures were identified on the basis of spectroscopic analysis.
RESULTEight compounds were isolated and identified as levistolide A (1), senkyunolide O (2), (3Z, 3Z')-6.8', 7.3'-diligustilide (3), tokinolide B (4), isotokinolide B (5), (3'Z)-(3R, 8S, 3a'R, 6'S)-3, 3a': 8, 6'-biligustilide (6), E, E'-3. 3', 8. 8'-diligustilide (7) and E, E'-3. 3', 8. 8'-isodiligustilide (8), which are all diligustilides.
CONCLUSIONCompound 7 was obtained from the plant for the first time; compounds 6 and 8 are new compounds.