Disseminated cryptococcal lymphadenitis with negative latex agglutination test.
- Author:
Xiao-Guang XU
1
;
Xin-Ling BI
;
Jian-Hua WU
;
Hong XU
;
Wan-Qing LIAO
Author Information
1. Department of Dermatology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
- Publication Type:Case Reports
- MeSH:
Adolescent;
Cryptococcus neoformans;
immunology;
pathogenicity;
Humans;
Latex Fixation Tests;
Lymphadenitis;
diagnosis;
immunology;
microbiology;
Male
- From:
Chinese Medical Journal
2012;125(13):2393-2396
- CountryChina
- Language:English
-
Abstract:
We reported an unusual case of disseminated cryptococcal lymphadenitis in an immunocompetent host who presented with fever and lymphadenopathy, which were the only two symptoms and signs. Latex agglutination test of serum and cerebrospinal fluid (CSF) were negative, while lymph node biopsy showed Cryptococcus neoformans. A diagnosis of disseminated cryptococcal lymphadenitis was made. Then the patient was treated with amphotericin B for 15 days as initial therapy and itraconazole for 6 months as maintenance therapy respectively. The patient received re-examination per 6 months and was followed up for 2 years. Swollen lymph nodes diminished gradually, and no fever or other symptoms were found. Latex agglutination test of serum and CSF were negative throughout the follow-up period, and anti-HIV, syphilis and tuberculosis antibody were all negative.
