The clinical evaluation of Oratest in detecting oral mucosal lesions.
- Author:
Bin CHENG
1
;
Linglan YANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adolescent; Adult; Aged; Carcinoma, Squamous Cell; diagnosis; Child; Coloring Agents; Female; Humans; Leukoplakia, Oral; diagnosis; Male; Mouth Mucosa; pathology; Mouth Neoplasms; diagnosis; Precancerous Conditions; diagnosis; Staining and Labeling; Tolonium Chloride
- From: West China Journal of Stomatology 2003;21(2):124-126
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEThe aim of the study was to evaluate the clinical efficacy of Oratest in detecting oral mucosal lesions.
METHODSSixty patients with oral mucosal lesions that were suspected as carcinoma or premalignant lesions were divided into two groups randomly. The lesions were stained with Oratest by topical application in one group and rinse application in another group. Staining results were recorded and compared with the pathological diagnosis.
RESULTSThe sensitivity of Oratest stain to oral carcinoma and dysplasia were 93.9% and 42.9%, respectively. The difference between rinse application and local application showed no significance(P > 0.01).
CONCLUSIONOratest can be used as a method of diagnosing squamous cell carcinoma of oral mucosa, but its reliability in screening oral pre-malignant lesions is still uncertain.
