The antitumor effectiveness of the compound of platin IV on the Swiss mice
- Author:
Quy Thi Nguyen
- Publication Type:Journal Article
- Keywords:
tumor
- MeSH:
Neoplasms;
mice;
therapeutics;
Pharmaceutical Preparations
- From:Pharmaceutical Journal
1999;274(2):21-23
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Dihydroxocisplatin [Pt(NH3Cl)2(OH)2] or compound of platin (IV)) has been synthesized and estimated its antitumor effectiveness on Swiss mice that affected with sarcoma TG180 ascitic tumor. The results showed that the compound of Platin(IV) reduced GR(%) to 14.7 (means inhibited 85.3% tumor development). The mitotic index of the tumor cells in experiments was twice lower than in control group
