The study on specific anti-Streptococcus mutans IgY against dental caries in rats.
- Author:
Mingwen FAN
1
;
Qianzhou JIANG
;
Zhuan BIAN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antibodies, Bacterial; administration & dosage; Dental Caries; prevention & control; Female; Immunization, Passive; Immunoglobulins; immunology; Male; Rats; Rats, Wistar; Streptococcal Vaccines; immunology; Streptococcus mutans; immunology
- From: West China Journal of Stomatology 2003;21(5):339-341
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of specific anti-streptococcus mutans IgY against streptococcus mutans on dental caries development in rats.
METHODS35 wistar rats were divided into 5 groups: group A received IgY gargle; group B received IgY lyophilized powder; group C received sterilized water as control; group D and E received egg yolk food with or without specific IgY individually. They were all fed with caries-inducing diet 2000#. The number of caries scores was counted by the procedure of Keyes'.
RESULTSThere was a significant lower mean of caries scores in groups treated with IgY lyophilized powder and gargle. By treating with egg-yolk food contained specific IgY, the mean of caries scores decreased comparing with no treatment group.
CONCLUSIONLocal passive immunization with specific anti-streptococcus mutans IgY may be an effective way to prevent the development of dental caries.
