Advances of sustained/controlled release pellets in traditional Chinese medicine.
- Author:
Li-Hua CHEN
1
;
Yi FENG
;
De-Sheng XU
Author Information
1. Center of Science and Technology, Shanghai University of Treditional Chinese Medicine, Shanghai 201203, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Capsules;
Delayed-Action Preparations;
chemistry;
Drug Delivery Systems;
Drugs, Chinese Herbal;
administration & dosage;
chemistry;
isolation & purification;
Humans;
Microspheres;
Plants, Medicinal;
chemistry;
Polyethylene Glycols;
chemistry;
Technology, Pharmaceutical;
methods
- From:
China Journal of Chinese Materia Medica
2007;32(6):472-475
- CountryChina
- Language:Chinese
-
Abstract:
Pellets are multiple-unit drug delivery system, which have good fluidity, release stability and uniformity. With preparation techniques and excipient materials gradually established, pellets play an important part in the development of sustained/controlled release drug delivery system. The recent advances in pellets including the release mechanism, preparation methods, excipients and the characteristics in vivo for the sustained/controlled release pellets in traditional Chinese medicine (TCM) were reviewed in order to provide the strategies and rational methods for further investigations and applications.
