Effects of Maidang Rutong granule on l-dopa-induced galactozemia in rats.
- Author:
Su-qin XU
1
;
Qiao-jun HE
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Animals, Newborn; Atrophy; Body Weight; drug effects; Drug Combinations; Drugs, Chinese Herbal; pharmacology; Female; Lactation; drug effects; Lactation Disorders; blood; chemically induced; physiopathology; Levodopa; Male; Mammary Glands, Animal; drug effects; pathology; Prolactin; blood; Random Allocation; Rats; Rats, Sprague-Dawley
- From: China Journal of Chinese Materia Medica 2007;32(8):722-725
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study galactagogue effect of Maidang Rutong granule on the lactation rats.
METHODThe experiments were designed to observe the efficiency of Maidang Rutong granule on lactescence, serum prolactin, and morphology of mammary gland with rat galactozemia model established by injecting l-dopa.
RESULTMaidang Rutong granule showed significant enhancement for lactescence and the offspring's body weight. It could antagonize the decrease of serum prolactin and the atrophy of mammary gland induced by l-dopa.
CONCLUSIONMaidang Rutong granule exhibited significant galactagogue effect on the l-dopa-induced galactozemia in rats.
