Investigation of organophosphorous insecticides residue in Chinese crude drugs.
- Author:
Jia-Lun WU
1
;
Xiu-Ping ZHAN
;
Yao-Hua ZOU
;
Shi-Fei CHEN
;
Guang-Zhao LU
;
Fu-Gen LAI
Author Information
- Publication Type:Journal Article
- MeSH: Atractylodes; chemistry; Chromatography, Gas; Chrysanthemum; chemistry; Curcuma; chemistry; Drug Contamination; Drugs, Chinese Herbal; chemistry; Fritillaria; chemistry; Organophosphorus Compounds; analysis; Pesticide Residues; analysis; Plants, Medicinal; chemistry
- From: China Journal of Chinese Materia Medica 2007;32(9):798-800
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study eleven organophosphorus insecticides residuals in four kinds of Chinese crude drugs.
METHODThe organophosphorus insecticides were extracted with dichloromethane and cleaned-up with a mixture of Celite 545-activated carbon. The extracts were analyzed by gas chromatography equipped with a flame photometric detector (FPD).
RESULTAnalysis of fortified Chinese crude drug showed that the average recoveries ranged from 77.5% -112.3% at three different levels, the RSDs were below 10% (n = 4). Trace organophosphorous pesticide residues were found in samples of Rhizoma Atractylodis Macrocephalae and Flos Chrysanthemi.
CONCLUSIONA method was established for determination multi-residues in Rhizma Atractylodis Macrocephalae, Radix Curcumae, Bulbus Fritillariae Thunbergii and Flos Chrysanthemi. It provides a method for the risk assessment of organophosphorous pesticide in Chinese crude drugs.
