Effect of early enteral nutrition on immune function of the patients after operation for severe abdominal trauma.
- Author:
Gong-hang DONG
1
;
Ju-fang CAI
;
Jun HAO
;
Qi-Guang ZHONG
;
Ying-jun LI
Author Information
- Publication Type:Journal Article
- MeSH: Abdominal Injuries; immunology; surgery; Adolescent; Adult; CD3 Complex; analysis; CD4 Antigens; analysis; CD4-CD8 Ratio; CD8 Antigens; analysis; Complement C3; analysis; Enteral Nutrition; Female; Humans; Immunoglobulin A; analysis; Immunoglobulin G; analysis; Male; Postoperative Period; Young Adult
- From: Chinese Journal of Gastrointestinal Surgery 2006;9(2):145-147
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the effect of early enteral nutrition (EN) on immune function of the patients after operation for severe abdominal trauma.
METHODSFourty patients who underwent operation for severe abdominal trauma were randomly divided into two groups, and received an early enteral nutrition (EN group, n=20) through jejunal nutritional tube from postoperative day 1, or parental nutrition (PN group, n=20) for 7 days. C3, IgA, IgM, IgG and CD3+, CD4+, CD8+, CD4+/CD8+ of the two groups patients were detected on the day before operation and the postoperative day 1 and 8. The infection complications were compared.
RESULTSAfter 7 days, the levels of C3+, IgA, IgG, CD3+, CD4+, CD8+, and CD4+/CD8+ in EN group increased significantly compared with those in PN group (P< 0.05). The incidence of infection was 10% in EN group, while 30% in PN group (P< 0.05).
CONCLUSIONEarly enteral nutrition can improve immune function and decrease postoperative infection after operation for severe abdominal trauma.
