Diagnostic of tuberculous meningitis of children by polymerase chain reaction (PCR)
- Author:
Ha Thu Nguyen
- Publication Type:Journal Article
- Keywords:
tuberculous meningitis
- MeSH:
Polymerase Chain Reaction;
Tuberculosis, Meningeal
- From:Journal of Medical Research
1998;8(4):28-32
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The PCR technique was used to identify ADN of M. Tuberculosis on cerebrospinal fluid samples in 44 tuberculous meningitis of children. The control group consists of other 21 meningitis (non Tuberculosis). The result showed that the PCR technique in finding M. Tuberculosis with the sensitivity is 68.2%, the negative predict value is 60%, the specificity and the positive predict value are all 100% respectively. The PCR result depended on patients who had been treated with tuberculosis drugs and had combined tuberculous injuries in the past. The PCR technique gives better results than other traditional M. Tuberculosis finding methods and even better than the ELISA technique
