Rubrofusarin glucosides of Berchemia polyphylla var. leioclada and their scavenging activities for DPPH radical.
- Author:
Yongshuai JING
1
;
Juan YANG
;
Lanfang WU
;
Zhendong ZHANG
;
Li FANG
Author Information
- Publication Type:Journal Article
- MeSH: Biphenyl Compounds; metabolism; Free Radical Scavengers; chemistry; pharmacology; Glucosides; chemistry; pharmacology; Nuclear Magnetic Resonance, Biomolecular; Picrates; metabolism; Pyrones; chemistry; pharmacology; Rhamnaceae; chemistry
- From: China Journal of Chinese Materia Medica 2011;36(15):2084-2087
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the rubrofusarin glucosides from whole plants of Berchemia polyphylla var. leioclada, and their scavenging activities for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical.
METHODThe chemical constituents were isolated and purified via repeated silica gel and Sephadex LH-20 column chromatography. Their structures were elucidated by spectral analysis and the compounds were tested for their scavenging activities on DPPH radical.
RESULTThree rubrofusarin glucosides compounds were isolated and identified as rubrofusarin-6-O-beta-D-glucopyranoside (1), rubrofusarin-6-O-beta-D-(6'-O-acetyl) glucopyranoside (2), rubrofusarin-6-O-alpha-L-rhamnosyl-(1-6) -O-beta-D-glucopyranside (3). Three isolated compounds showed strong scavenging activities on DPPH radical, the concentration of half elimination ratio( micromol x L(-1)) of VitC and Compounds 1-3 were 18.2, 40.5, 23.3 and 13.6, respectively.
CONCLUSIONCompounds 1-3 were isolated from this plant for the first time and compound 2 was a new compound. They showed significant antioxidant activity, and the scavenging activity of compound 3 was a little stronger than that of VitC.
