Diterpenoids from Chinese eaglewood.
- Author:
Lin YANG
1
;
Lirui QIAO
;
Dan XIE
;
Jungui DAI
;
Shunxing GUO
Author Information
1. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China.
- Publication Type:Journal Article
- MeSH:
Diterpenes;
chemistry;
isolation & purification;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Plants, Medicinal;
chemistry;
Thymelaeaceae;
chemistry
- From:
China Journal of Chinese Materia Medica
2011;36(15):2088-2091
- CountryChina
- Language:Chinese
-
Abstract:
Column chromatography on silica gel, Sephadex LH-20, semi-preparative HPLC were used to separate and purify the compounds from the petroleum ether and ethanol extract of Chinese eaglewood. Nine compounds were isolated. On the basis of their spectroscopic data, their structures were identified as dehydroabietic acid (1), methyl dehydroabietate (2), methyl 7-oxodehydroabietate (3), 7alpha, 15-dihydroxydehydroabietic acid (4), 7alpha-hydroxypodocarpen-8(14)-en-13-on-18-oic acid (5), pimaric acid (6), pimarol (7), 18-norpimara-8 (14), and 15-dien-4alpha-ol (8), 18-norisopimara-8 (14), 15-dien-4beta-ol (9). All of the compounds were isolated from this plant for the first time, and compounds 5, 8 and 9 are norditerpenoids.
