Studies on chemical constituents of Rabdosia serra.

Author: Qin ZHENG ¹ ; Jiongmo CUI ; Hongzheng FU
Author Information

1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Publication Type:Journal Article
MeSH: Isodon; chemistry
From: China Journal of Chinese Materia Medica 2011;36(16):2203-2206
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the chemical constituents of aerial part of Rabdosia serra.
METHODThe compounds were isolated by extraction, coloum chromatography over silica gel and ODS, and preparative HPLC. Their structures were identified by various spectroscopic methods including MS, IR, 1D and 2D NMR data.
RESULTSix compounds were isolated from R. serra and were characterized as ent-1alpha, 7alpha, 14beta, 20-tetrahydroxy-11, 16-kauradien-15-one (1), kamebakaurin (2), dihydrokamebakaurin (3), rabdoinflexin A (4), daucosterol( 5), and beta-sitosterol (6).
CONCLUSIONCompound 1 is a new compound, and coumpound 3 was obtained from this plant for the first time.