Chemical constituents of Swertia hispidicalyx.
- Author:
Fuqiang JIANG
1
;
Xuemei ZHANG
;
Yunbao MA
;
Chang'an GENG
;
Zhiyong JIANG
;
Jijun CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Antiviral Agents; isolation & purification; pharmacology; Hepatitis B virus; drug effects; Swertia; chemistry
- From: China Journal of Chinese Materia Medica 2011;36(16):2215-2218
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Swertia hispidicalyx.
METHODThe EtOAc part of S. hispidicalyx was chromatographied by various column chromatography methods, and the isolates were identified based on spectroscopic analyses (MS, 1H-and 13C-NMR).
RESULTEleven compounds were isolated from S. hispidicalyx and characterized as 1,3,5,8-tetrahydroxyxanthone (1), 1,5,8-trihydroxy-3-methoxyxanthone (2), gentiolactone (3), swertiamarin (4), 3,4-dihydro-1H,6H,8H-naphtho [1, 2-c:4, 5-c', d'] dipyrano-1,8-dione (5), (+)-syringaresinol (6), trans-coniferyl aldehyde (7), maslinic acid (8), oleanolic acid (9), daucosterol (10), and -sitosterol (11).
CONCLUSIONCompounds 1-11 were obtained from S. hispidicalyx for the first time.
