Research progress of salvianolic acid A.
- Author:
Li ZHANG
1
;
Weiku ZHANG
;
Ying ZHAO
;
Xiuying YANG
;
Lianhua FANG
;
Shoubao WANG
;
Lili SHI
;
Xiaoyan YU
;
Subo WANG
;
Haiguang YANG
;
Jialin SUN
;
Shuo TIAN
;
Guanhua DU
Author Information
1. Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Biomedical Research;
Caffeic Acids;
chemistry;
isolation & purification;
pharmacology;
Drug Therapy;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
pharmacology;
Humans;
Lactates;
chemistry;
isolation & purification;
pharmacology;
Molecular Structure;
Salvia miltiorrhiza;
chemistry
- From:
China Journal of Chinese Materia Medica
2011;36(19):2603-2609
- CountryChina
- Language:Chinese
-
Abstract:
Salvianolic acid A is a water-soluble component from Danshen, which is frequently used in traditional Chinese medicine. High performance liquid chromatography was often used to analyze content of salvianolic acid A. The yield of salvianolic acid A increased by the technological improvement of extraction and separation. Salvianolic acid A possessed multiple pharmacological activities, including antioxidants, myocardial ischemic protection, antithrombatic, neuroprotection, anti fibrosis, prevention of diabetes and complications. Recently, preliminary pharmacokinetics characteristics of salvianolic acid A were clarified. Based on the research literature and study work from author's laboratory, this review will focus on recent developments concerning the chemistry, pharmacology and pharmacokinetic of salvianolic acid A, and prospect further research.
