Antibiotic Susceptibilities of Ocular Isolates from Patients with Bacterial Ke ratitis: A Multi-center Study.
- Author:
Young Ho HAHN
1
;
Sang Joon LEE
;
Tae Won HAHN
;
Hungwon TCHAH
;
Jae Chan KIM
Author Information
1. Department of Ophthalmology, Gospel Hospital, The Kosin University, Pusan, Korea.
- Publication Type:Multicenter Study ; Original Article
- Keywords:
Antibiotics;
Bacterial keratitis;
Sensitivity test
- MeSH:
Anti-Bacterial Agents;
Cefoperazone;
Ceftazidime;
Ciprofloxacin;
Clindamycin;
Coagulase;
Gentamicins;
Humans;
Keratitis;
Penicillins;
Piperacillin;
Prospective Studies;
Pseudomonas aeruginosa;
Serratia;
Staphylococcus;
Staphylococcus aureus;
Streptococcus;
Streptococcus pneumoniae;
Teicoplanin;
Vancomycin
- From:Journal of the Korean Ophthalmological Society
1999;40(9):2401-2410
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This multi-center study was performed prospectively to evaluate the causative organisms and antibiotic sensitivity of isolates in bacterial keratitis from April 1995 to December 1998. Total number of infectious keratitis was 1002 cases. Among them,279 cases were confirmed with bacterial keratitis and 314 strains were identified. Major causative organisms of bacterial keratitis were Pseudomonas aeruginosa 121 strains (38.54%), coagulase negative staphylococcus (CNS) 34 strains (10.83%), Streptococcus pneumoniae 19 strains (6.81%), Staphylococcus aureus 18 strains (5.73%), and Serratia marscence 16 strains (5.10%). P.aeruginosa was highly sensitive to ciprofloxacin, ceftazidime, piperacillin, cefoperazone, imipenem,tobramicin,and gentamycin. Coagulase negative streptococcus showed high sensitivity to vancomycin, teicoplanin, clindamycin, and ciplofloxacin, but low sensitivity to penicillin and gentamycin. In conclusion, the choice of the effective antibiotics in the treatment of bacterial keratitis were essential to decrease resistant bacterial strains.
