Meta-analysis of the effectiveness of plasma exchange in treatment of severe and acute organophosphate poisoning.
- Author:
Hao-min QIU
1
;
Shu-cong ZHENG
;
Wei-guo WAN
;
He-jian ZOU
Author Information
- Publication Type:Journal Article
- MeSH: Humans; Organophosphate Poisoning; therapy; Pesticides; poisoning; Plasmapheresis
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2011;29(10):779-781
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo discuss the effectiveness of severe and acute organophosphate poisoning (AOPP) treated with plasma exchange in China.
METHODSResearches about effectiveness of severe AOPP treated with plasma exchange were analyzed by Review Manager 4.2 and fixed effect model of meta-analysis method were used.
RESULTSSix trials including 433 patients were identified. Treatment group including 211 patients adopted traditional physician therapy plus plasma exchange, and control group including 222 patients received physician therapy only. The case-fatality rate of the treatment group was lower than the control one [RR=0.30, 95%CI (0.19-0.49), P<0.01].
CONCLUSIONPlasma exchange can improve the cure rate of severe AOPP.
