Effect of tiaozhi yanggan decoction in treating patients with non-alcoholic fatty liver.
- Author:
Can-li GU
1
;
Yun-ke ZHANG
;
Yue-xiao FU
;
Shao-feng YANG
;
Xin-qiang LI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Body Mass Index; Body Weight; drug effects; Drugs, Chinese Herbal; adverse effects; therapeutic use; Fatty Liver; blood; drug therapy; physiopathology; Female; Humans; Lipids; blood; Liver; physiopathology; Male; Medicine, Chinese Traditional; adverse effects; methods; Middle Aged; Phytotherapy; adverse effects; Treatment Outcome
- From: Chinese journal of integrative medicine 2007;13(4):275-279
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo observe the clinical efficacy and safety of Tiaozhi Yanggan Decoction (TZYGD) in treating non-alcoholic fatty liver.
METHODSOne hundred and thirty-eight patients were enrolled and randomized into two groups according to the random number table in a ratio of 3:1, with 8 cases eventually dropping out. The symptoms, signs, liver function markers, blood lipids, iconographic indices and clinical comprehensive efficacy after a 12-week treatment course were assessed in 101 patients treated with TZYGD in the treated group and 29 patients treated with Thiola in the control group.
RESULTSThe total effective rate in the treated group and the control group was 81.19% and 68.97%, respectively, showing a significant difference between the two groups with the former being significantly higher than the latter (P<0.05). Moreover, the improvements in the symptoms, signs, liver function, blood lipids and iconographic indices in the treated group were favorable with no serious adverse reactions.
CONCLUSIONTZYGD is effective and highly safe in treating non-alcoholic fatty liver.
