Experimental study on effect of the water extract of dogwood fruits on the liver and testis in rats model of kidney-yang deficiency.
- Author:
Chun-sheng LI
1
;
Guo-xi ZHANG
;
Ti-ren SHI
;
Xiao-xia DONG
;
Pi SUN
;
Dian-dong LI
;
Hong-zhang XU
;
Ke-ji CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cornus; chemistry; Drugs, Chinese Herbal; isolation & purification; pharmacology; Fruit; chemistry; Hydrocortisone; Kidney Diseases; chemically induced; metabolism; pathology; Liver; metabolism; pathology; Liver Glycogen; metabolism; Male; Malondialdehyde; metabolism; Plants, Medicinal; chemistry; RNA; metabolism; Random Allocation; Rats; Rats, Wistar; Testis; metabolism; pathology; Yang Deficiency; chemically induced; metabolism; pathology
- From: China Journal of Chinese Materia Medica 2003;28(8):743-746
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the effect of Dogwood fruits on tonifying kidney-yang.
METHODThe effect of the water extract of Dogwood fruits on rats model of kidney-yang deficiency with the hydrocortisone was observed.
RESULTThe water extract of Dogwood fruits could make normal the liver weight, and mitigate hepatocyte pathologic changes, increase the heptocellular levels of RNA and hepatin, and decrease the malondialdehyde (MDA) in rats model of kidney-yang deficiency. It could also make the viscera quotiety return to normal way and increase the levels of RNA in the interstitial cells of testicle in rats model of kidney-yang deficiency.
CONCLUSIONWater extract of Dogwood fruits can protect and improve the functions of the liver and testicle in rats model of kidney-yang deficiency.
