Analysis of anthraquinones in serum and urine after oral administration of semen Cassiae.
- Author:
Xu-e LI
1
;
Wei MA
;
Bao-jiang GUO
;
Zhi ZENG
Author Information
- Publication Type:Journal Article
- MeSH: Administration, Oral; Animals; Anthraquinones; blood; urine; Cassia; chemistry; Drugs, Chinese Herbal; administration & dosage; isolation & purification; pharmacokinetics; Humans; Male; Plants, Medicinal; chemistry; Random Allocation; Rats; Rats, Sprague-Dawley; Seeds; chemistry; Species Specificity
- From: China Journal of Chinese Materia Medica 2003;28(9):849-851
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analysie the anthraquinones absorbed into serum by different animals (or human beings) after oral administration of Semen Cassiae.
METHODAnthraquinones in serum and urine of rats and urine of healthy men after taking Semen Cassiae orally were detected with HPLC.
RESULTOnly some of the anthraquinones were absorbed into serum. There were differences in absorption and metabolism of anthraquinones between rats and men and some new anthraquinones were produced in the process.
CONCLUSIONAnthraquinones absorbed into serum by the experimental animals or men should become target for researching into active compounds of anthraquinones in Semen Cassiae.
