The relationship between the protection of ginsenoside for spinal cell and nitric oxide.
- Author:
Shu-yi PAN
1
;
Xiao-wen PAN
;
Su-ping WANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cells, Cultured; Fetus; Ginsenosides; isolation & purification; pharmacology; Motor Neurons; cytology; drug effects; metabolism; Neurons, Afferent; cytology; drug effects; metabolism; Neuroprotective Agents; pharmacology; Nitric Oxide; metabolism; Panax; chemistry; Plants, Medicinal; chemistry; Rats; Rats, Sprague-Dawley; Spinal Cord; cytology; metabolism
- From: China Journal of Chinese Materia Medica 2003;28(9):851-853
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the relationship between the protection of Ginsenoside(GS) for spinal cells and nitric oxide (NO).
METHODSpinal cells were cultured in vitro, the model of peripheral nerve was established by scarifying the cells, and NO was measured by Griess method.
RESULTNO in injury group was high than that in noninjury group and NO in group cultured by GS was less than that in group cultured by common medium.
CONCLUSIONNO increases when peripheral nerve is injuried, and the protective effect of GS on spinal cells may be through inhibiting NO release.
