Study on the preparation of rapid-dissoluted EGb droppills.
- Author:
Yue-bin GE
1
;
Da-wei CHEN
;
Zhi-bo LI
;
Yan MA
;
Hua-xian SONG
;
Hai-yang HU
Author Information
- Publication Type:Journal Article
- MeSH: Drug Stability; Drugs, Chinese Herbal; administration & dosage; chemistry; isolation & purification; Flavonoids; analysis; Ginkgo biloba; chemistry; Plants, Medicinal; chemistry; Solubility; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2003;28(5):410-413
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the formulation and technique of preparation of rapid-dissoluted EGb (Extract of Ginkgo biloba) droppills.
METHODTaking the dissolution percentage of total flavonoids in EGb and weight variation as index, the formulation and technique of EGb droppills were optimized by the orthogonal experiment.
RESULTT50 was 3.62 min and mean weight variation was 2.80%.
CONCLUSIONRapid-dissoluted EGb droppills can increase the dissoluting rate distinctly and reach the purpose of preparation.