Isolation and identification of the ligustilide compounds from the root of Angelica sinensis.
- Author:
Xin-hua LU
1
;
Hong LIANG
;
Yu-ying ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: 4-Butyrolactone; analogs & derivatives; chemistry; isolation & purification; Angelica sinensis; chemistry; Benzofurans; chemistry; isolation & purification; Molecular Structure; Plant Roots; chemistry; Plants, Medicinal; chemistry
- From: China Journal of Chinese Materia Medica 2003;28(5):423-425
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo find out substance basis of pharmacological activities of Angelica sinensis.
METHODChromatographic methods were used to isolate the chemical components, and spectroscopic methods were used to identify their structures.
RESULTFive compounds were isolated from the ethanol extract of the roots of Angelica sinensis. Their structures were identified as: (Z)-ligustilide, (Z)-6,7-epoxyligustilide, (Z)-6,7-cis-dihydroxyligustilide, (E)-6,7-cis-dihydroxy-ligustilide and 11-angeloylsenkyunolide F.
CONCLUSION11-angeloylsenkyunolide F was obtained from Angelica sinensis for the first time.
