Clinical pathological analysis and immunohistochemical study of ten solitary fibrous tumors.
- Author:
Huiping WANG
1
;
Wei ZHANG
;
Liping YAN
;
Hongtian YAO
;
Wei DING
;
Xinru YU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Antigens, CD34; analysis; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Male; Microscopy, Electron; Middle Aged; Neoplasms, Fibrous Tissue; chemistry; diagnostic imaging; pathology; Proto-Oncogene Proteins c-bcl-2; analysis; Ultrasonography; Vimentin; analysis
- From: Chinese Medical Journal 2002;115(9):1412-1414
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo study the clinical and pathological characteristics of solitary fibrous tumor (SFT).
METHODSClinical pathological analysis and immunohistochemical studies were performed on ten patients with SFT.
RESULTSThe SFTs located variously and showed different histological features. All cases showed positive staining for CD(34), VM (vimentin) and Bcl-2, but negative staining for Desmin, S-100, CK (cytokeratin) and EMA (epithelial membrane antigen).
CONCLUSIONSSFT is described as a "patternless" growth pattern. According to clinical pathological features and immunohistochemistry, it is different from other soft tissue tumors. Long-term clinical follow-up is necessary for this kind of tumor.