Amides from the stems of Uvaria kweichowensis.
- Author:
Qiong-ming XU
1
;
Yan-li LIU
;
Bao-hua ZHAO
;
Li-zhen XU
;
Shi-lin YANG
;
Shao-hua CHEN
Author Information
1. College of Pharmacy, Soochow University, Suzhou 215123, China.
- Publication Type:Journal Article
- MeSH:
Amides;
chemistry;
isolation & purification;
Aristolochic Acids;
chemistry;
isolation & purification;
Magnetic Resonance Spectroscopy;
Molecular Structure;
Plant Stems;
chemistry;
Plants, Medicinal;
chemistry;
Spectrometry, Mass, Electrospray Ionization;
Uvaria;
chemistry
- From:
Acta Pharmaceutica Sinica
2007;42(4):405-407
- CountryChina
- Language:Chinese
-
Abstract:
Uvaria kweichowensis is a folk nongovernmental herb used to treat cure inflammation and tumour in the Southwest area of China. During the course of our investigation for antitumour agents from the stems of Uvaria kweichowensis, six amides were obtained by means of solvent extraction, chromatography on silica gel and Sephadex LH-20 repeatedly. And their structures were identified as uvariadiamide (1), cepharanone (2), aristololactam A II (3), enterocarpam II (4), aristololactam A Ia (5), and 4,5-dioxodehydroasimilobine (6) on the basis of chemical methods and spectral analyses (EI-MS, 1H NMR, 13C NMR). Among them, compound 1 is a new compound; the other compounds were obtained from this plant for the first time.
