Identification of Puumala like viruses in China.

Author: Gang LIU ¹ ; Chuan LI ; Guang-wei HU ; Yue LI ; Lai-shun YAO ; Yu-qing CHEN ; Biao HUANG ; Ming REN ; Yun-zhi CHEN ; Shi-xin GUAN ; Chuan-you YU ; Bao-zhong NA ; Xiang-dong ZHONG ; Yue-xin SUN ; Wen-xue LI ; De-xin LI
Author Information

1. Department of Viral Hemorrhagic Fever and Ercephalitis. Institute of Viral Diseases Control and Prevention, China Center for Disease Control and Prevention, Beijing, 100052 China.
Publication Type:Journal Article
MeSH: Animals; China; DNA, Viral; analysis; Hemorrhagic Fever with Renal Syndrome; virology; Lung; virology; Mice; Phylogeny; Puumala virus; isolation & purification; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid
From: Chinese Journal of Experimental and Clinical Virology 2003;17(1):55-57
CountryChina
Language:Chinese
Abstract:
BACKGROUNDTo confirm if Puumala like viruses exist in China.
METHODSRNA was extracted from lungs of bank voles captured in the Northeast China, partial S segments genome of Puumala viruses were amplified and sequenced.
RESULTS926 bp cDNA of S segments of Puumala like virus was amplified and sequenced. The phylogenetic analysis revealed that the Puumala like viruses found in China were most close to that found in Far East region of Russia.
CONCLUSIONSPuumala like virus does exist in Northeast China, and the nucleotides sequence of the viruses have high homolog to Puumala viruses found in Russia.