Changes of blood cells in patients with severe acute respiratory syndrome.
- Author:
Tian-jun JIANG
1
;
Min ZHAO
;
Zhi-ping ZHOU
;
Xian-zhi ZHOU
;
Yuan-li MAO
;
Zhi-guo LIU
;
Wei HONG
;
Yang-xin XIE
;
Hui-ying YAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Early Diagnosis; Female; Humans; Leukocyte Count; Leukocytes; cytology; Male; Middle Aged; Prognosis; Severe Acute Respiratory Syndrome; diagnosis
- From: Chinese Journal of Experimental and Clinical Virology 2003;17(4):344-345
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the changes of blood corpuscles of patients with severe acute respiratory syndrome (SARS) in Beijing.
METHODSTotally 43 patients (21 male and 22 female, 19-74 years old age range) diagnosed as of probable SARS were included in this study. Their corpuscles in the peripheral blood were tested every two days, and the results were analyzed.
RESULTSPatients with SARS were more likely to develop leukocytopenia, lymphopenia and thrombocytopenia in the early period of disease than those in control group. The situation, especially lymphopenia and thrombocytopenia, could not be reversed in patients who died. Persistent low counts of lymphocytes and platelets at presentation might be associated with adverse outcomes.
CONCLUSIONLow counts of leukocytes, lymphocytes and platelets were common among patients in the early stage of SARS. Persistent Lymphopenia and thrombocytopenia may be associated with the prognosis.