Predictors associated with clinical deterioration in SARS patients.
- Author:
Jie YAN
1
;
Xin FENG
;
Jing-hua TIAN
;
Yao XIE
;
Jun YAO
;
Zhong-ping HE
;
Dao-zhen XU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Disease Progression; Female; Humans; Logistic Models; Lymphopenia; virology; Male; Middle Aged; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Random Allocation; SARS Virus; Severe Acute Respiratory Syndrome; complications; diagnosis; immunology; virology
- From: Chinese Journal of Experimental and Clinical Virology 2003;17(3):222-224
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUNDTo study the predictive factors associated with clinical deterioration in SARS patients.
METHODSThe clinical data of 60 SARS patients were analyzed by logistic regression and Cox's proportional hazards analysis.
RESULTSIn logistic regression models, both older age (P=0.009) and severe lymphopenia (P=0.004) were significant predictors of clinical deterioration. In Cox's proportional hazard models, severe lymphopenia was significant predictor associated with prolongation of stay in hospital.
CONCLUSIONOlder age and severe lymphopenia seem to be statistically significant for predicting the clinical deterioration in SARS patients.