Study on HPLC-FPS of raw and processed fructus polygoni orientalis.
- Author:
Yanjun ZHAI
1
;
Min ZHAO
;
Hui ZHANG
;
Zhengyun CHU
;
Tingguo KANG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; methods; Drug Contamination; prevention & control; Drugs, Chinese Herbal; analysis; chemistry; Plant Extracts; analysis; chemistry; Quality Control; Quercetin; analogs & derivatives; analysis; Reference Standards; Spectrometry, Mass, Electrospray Ionization; methods
- From: China Journal of Chinese Materia Medica 2010;35(6):711-713
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo establish the HPLC fingerprint method of Fructus Polygoni Orientalis before and after processed by choosing taxifolin as reference to compare the changes of chemical composition.
METHODHPLC method was emplyed with a gradient elution phase in a flow rate of 1 mL x min(-1) and the detection wavelength of 270 nm.
RESULTTwenty marker peaks were marked out in the raw samples and 33 marker peaks in the processed product. Methodology met was consistent with the requirement, similarity was exceeded 0.9.
CONCLUSIONThis method is stationary, precise and feasible, which provide references of quality control for Fructus Polygoni Orientalis.
