Dihydroflavones in Rhododendron concinnum.
- Author:
Lei ZHAO
1
;
Dinghui WU
;
Xiaohui YU
;
Yan ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Antineoplastic Agents, Phytogenic; pharmacology; Cell Line, Tumor; Cell Survival; drug effects; Chromatography, High Pressure Liquid; methods; Chromones; chemistry; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Quercetin; analogs & derivatives; analysis; pharmacology; Rhododendron; chemistry; Silica Gel; Silicon Dioxide; analysis; pharmacology
- From: China Journal of Chinese Materia Medica 2010;35(6):722-724
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of the whole plant of Rhododendron concinnum.
METHODThe compounds were isolated and purified by chromatography on silica gel and polyamide. Their structures were identified on the basis of spectroscopic data (MS,1H-NMR and 13C-NMR) and chemical evidence.
RESULTFive dihydroflavones were isolated and identified as (2R)-farrerol-7-O-glucopyranoside (1), (2R,3R)-(-)-dihydroquercetin-3-O-beta-D-xylopyranoside(2), (2S,3S)-(-)-dihydroquercetin-3-O-beta-D-glucopyranoside(3), eriodictyol-7-O-beta-D-glucopyranoside (4) , (2R, 3R)-(+)-dihydroquercetin (5).
CONCLUSIONExcept compound 5, others were firstly isolated from the genus Rhododendron.
