Application of Preoperative CT/MRI Image Fusion in Target Positioning for Deep Brain Stimulation.
- Author:
Yu WANG
1
;
Zi-Yuan LIU
1
;
Wan-Chen DOU
1
;
Wen-Bin MA
1
;
Ren-Zhi WANG
1
;
Yi GUO
1
Author Information
1. Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730 China.
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Deep Brain Stimulation;
adverse effects;
methods;
Dystonia;
therapy;
Female;
Humans;
Magnetic Resonance Imaging;
Male;
Middle Aged;
Parkinson Disease;
therapy;
Retrospective Studies;
Tomography, X-Ray Computed
- From:
Chinese Medical Sciences Journal
2016;31(3):161-167
- CountryChina
- Language:English
-
Abstract:
Objective To explore the efficacy of target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation.Methods We retrospectively analyzed the clinical data and images of 79 cases (68 with Parkinson's disease, 11 with dystonia) who received preoperative CT/MRI image fusion in target positioning of subthalamic nucleus in deep brain stimulation. Deviation of implanted electrodes from the target nucleus of each patient were measured. Neurological evaluations of each patient before and after the treatment were performed and compared. Complications of the positioning and treatment were recorded.Results The mean deviations of the electrodes implanted on X, Y, and Z axis were 0.5 mm, 0.6 mm, and 0.6 mm, respectively. Postoperative neurologic evaluations scores of unified Parkinson's disease rating scale (UPDRS) for Parkinson's disease and Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) for dystonia patients improved significantly compared to the preoperative scores (P<0.001); Complications occurred in 10.1% (8/79) patients, and main side effects were dysarthria and diplopia.Conclusion Target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation has high accuracy and good clinical outcomes.
