Status quo and prospects for genetic studies on type 2 diabetes.
- Author:
Li-nong JI
1
Author Information
1. Peking University Diabetes Center, Beijing 100044, China. jiln@bjmu.edu.cn
- Publication Type:Journal Article
- MeSH:
Diabetes Mellitus, Type 2;
genetics;
Environment;
Genetic Predisposition to Disease;
Genetic Research;
Humans;
Insulin Resistance;
genetics
- From:
Acta Academiae Medicinae Sinicae
2006;28(2):278-283
- CountryChina
- Language:Chinese
-
Abstract:
Type 2 diabetes is the main type of diabetes in diabetic population. Along with the rapid changes of life style and increased life expectancy, the prevalence of type 2 diabetes increases rapidly worldwide. However, strong evidences have shown that genetic factors play important roles in the pathogenesis of type 2 diabetes, except for some rare subtypes of type 2 diabetes. The genetic patterns of the common forms of type 2 diabetes do not follow the role of classic Mendelian inheritance. Therefore, the type 2 diabetes is regarded as a complex disease caused by interaction between gene and environment. However, little progress has been made during past two decades in the genetic epidemiology of type 2 diabetes. This article reviews the current status of genetic epidemiology of type 2 diabetes and proposes strategies for future researches.
