Quantitative analysis of electroencephalograph in depression based on phase synchronization.
- Author:
Qiaoli HU
1
Author Information
1. Department of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240. qiaolihu15@gmail.com
- Publication Type:Journal Article
- MeSH:
Adult;
Aged;
Case-Control Studies;
Depression;
physiopathology;
Electroencephalography;
Female;
Humans;
Male;
Middle Aged;
Signal Processing, Computer-Assisted;
Young Adult
- From:
Chinese Journal of Medical Instrumentation
2010;34(4):246-249
- CountryChina
- Language:Chinese
-
Abstract:
EEG signals of depression patients and normal control subjects under the states of closed eyes and mental arithmetic are investigated through the method of phase synchronization (PS) analysis. Compared with conventional quantitative EEG (qEEG) analysis, PS analysis is a powerful method which can detect the weak interaction between signals by quantifying the relationship of the instantaneous phases of the signals but excluding the influence of the amplitudes. Results suggest that the global PS index of depression in the two states are much lower than that of controls, and the left hemispheric and the inter-hemispheric PS indices of depression show significant difference from that of controls, while the right hemispheric PS index shows no significant difference between these two groups.