Rapid detection device of bacteria drug-sensitivity using electrical impedance method.
- Author:
Hongzhi WANG
1
;
Xiaofeng PANG
;
Aihua WANG
Author Information
1. Biological Electro Magnetic and Bioelectronic Technological Key Laboratory of Sichuan Province, College of Life science and Technology, Electron Scientific and Technological University, Chengdu 610054, China.
- Publication Type:Journal Article
- MeSH:
Bacteria;
drug effects;
Electric Impedance;
Equipment Design;
Microbial Sensitivity Tests;
instrumentation;
methods
- From:
Chinese Journal of Medical Instrumentation
2010;34(5):326-329
- CountryChina
- Language:Chinese
-
Abstract:
Since the bacteria metabolites in the process of growth and reproduction of can lower the resistivity characteristics of the medium, the electrical impedance method can develop a rapid detection device of bacterial drug sensitivity. The device consists of micro-organisms impedance sensors, computer systems, signal generator, resistance Anti-detection circuit, the time allocation controller, constant temperature incubator and auxiliary circuits and other components. It measures the electrical impedance of the medium, and bacteria in the culture period to obtain the impedance value of the monitor into the impedance curve. Drug sensitivity of bacteria can be determined, using this form of differential impedance curve. This detection device significantly shortened the time of bacterial drug susceptibility testing, achieving rapid drug susceptibility testing of clinical medicine, drug susceptibility testing automation and intelligence.
