Research progress on IR improvement and acting mechanisms of active ingredients of traditional Chinese medicine.
- Author:
Hua ZHENG
1
;
Yanru GE
Author Information
1. School of Pharmacological Science, Jiangsu University, Zhenjiang 212013, China. zhenghuas08@126.com
- Publication Type:Journal Article
- MeSH:
Animals;
Diabetes Mellitus, Type 2;
complications;
drug therapy;
physiopathology;
Drugs, Chinese Herbal;
analysis;
therapeutic use;
Humans;
Insulin Resistance;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2010;35(4):531-535
- CountryChina
- Language:Chinese
-
Abstract:
The insulin resistance (IR) and the active ingredients of traditional Chinese medicine and their mechanisms to improve IR in the last 3 years are summarized. Retrieve, classify and arrange the recent documentations of china and abroad. IR can drive the occurrence and progress of type 2 diabetes mellitus (T2DM), and there are several molecular mechanisms for the occurrence of IR. IR has been a research focus of diabetes, the control strategies of T2DM have been changed from the "hypoglycemic therapy" into "improve the IR and IR-related metabolic abnormalities, and make a comprehensive prevention and treatment of cardiovascular risk factors". It is demonstrated by experiments that a variety of active ingredients of traditional Chinese medicine can improve IR through different mechanisms to treat diabetes mellitus.
