Impact of mechanical stress and tension-stress on angiogenesis in wound healing.
- Author:
Hai-Qiang WANG
1
;
Li ZHAO
Author Information
1. PLA Institute of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Neovascularization, Physiologic;
Stress, Mechanical;
Wound Healing;
physiology;
Wounds and Injuries;
physiopathology;
therapy
- From:
Chinese Journal of Traumatology
2006;9(2):118-124
- CountryChina
- Language:English
-
Abstract:
Angiogenesis plays a fundamental role in the development of the embryonic vascular tree as well as in several normal and pathologic conditions during postnatal life. Blood supply, established by neovascularization, is imperative for histogenesis during wound healing as well as the limb lengthening applied extensively in the treatment of skeletal trauma sequalae. But little attention has been paid to this area. This review aims to summarize angiogenesis regulation, the process of angiogenesis in wound healing and angiogenesis under mechanical stress, particularly in association with the tension-stress principle.
