Influence of Diaphragmatic Mobility on Hypercapnia in Patients with Chronic Obstructive Pulmonary Disease.
10.3346/jkms.2011.26.9.1209
- Author:
Hyun Wook KANG
1
;
Tae Ok KIM
;
Bo Ram LEE
;
Jin Yeong YU
;
Su Young CHI
;
Hee Jung BAN
;
In Jae OH
;
Kyu Sik KIM
;
Yong Soo KWON
;
Yu Il KIM
;
Young Chul KIM
;
Sung Chul LIM
Author Information
1. Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea. lscmd@jnu.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Pulmonary Disease, Chronic Obstructive;
Diaphragm mobility;
Hypercapnia;
Ultrasonography
- MeSH:
Aged;
Airway Resistance/physiology;
Carbon Dioxide/blood/physiology;
Diaphragm/physiopathology/*ultrasonography;
Female;
Humans;
Hypercapnia/complications/*physiopathology;
Male;
Middle Aged;
Portal Vein;
Pulmonary Disease, Chronic Obstructive/complications/*physiopathology/ultrasonography;
Pulmonary Gas Exchange;
Respiratory Muscles/physiopathology
- From:Journal of Korean Medical Science
2011;26(9):1209-1213
- CountryRepublic of Korea
- Language:English
-
Abstract:
A reduction in diaphragm mobility has been identified in patients with chronic obstructive pulmonary disease (COPD) and has been associated with a decline in pulmonary function parameters. However, little information exists regarding the potential role of diaphragm mobility on hypercapnia in COPD. A new method of assessing the mobility of the diaphragm, using ultrasound, has recently been validated. The purpose of the present study was to investigate the relationship between diaphragm mobility and pulmonary function parameters, as well as that between arterial blood gas values and diaphragm mobility, in COPD patients. Thirty seven COPD patients were recruited for pulmonary function test, arterial blood gas analysis and diaphragm mobility using ultrasound to measure the craniocaudal displacement of the left branch of the portal vein. There were significant negative correlations between diaphragmatic mobility and PaCO2 (r = -0.373, P = 0.030). Diaphragmatic mobility correlated with airway obstruction (FEV1, r = 0.415, P = 0.011) and with ventilatory capacity (FVC, r = 0.302, P = 0.029; MVV, r = 0.481, P = 0.003). Diaphragmatic mobility also correlated significantly with pulmonary hyperinflation. No relationship was observed between diaphragm mobility and PaO2 (r = -0.028, P = 0.873). These findings support a possibility that the reduction in diaphragm mobility relates to hypercapnia in COPD patients.
