Structure and function of 3'- untranslated region in picornavirus.
- Author:
Rui-Ying LIANG
;
Chuan-Feng LI
;
Chun-Chun MENG
;
Zong-Yan CHEN
;
Guang-Qing LIU
- Publication Type:Journal Article
- MeSH:
3' Untranslated Regions;
Animals;
Humans;
Nucleic Acid Conformation;
Picornaviridae;
chemistry;
genetics;
metabolism;
Picornaviridae Infections;
virology;
RNA, Viral;
chemistry;
genetics;
metabolism
- From:
Chinese Journal of Virology
2014;30(4):463-469
- CountryChina
- Language:Chinese
-
Abstract:
Both sides of the picornavirus genome have 5'-untranslated region (5'UTR) and 3'- untranslated region (3'UTR). This study demontrated that both the 5'-and 3'-UTR can form complex structures, such as stem-loop, clover and pseudoknot structure, These structures play an important role in the regulaton of the replication and translation of the viruses. This article reviewed the progress of research on the structure and function of picornavirus' 3'-UTR over recent years.
