Stem cell niche and its roles in proliferation and differentiation of stem cells.
- Author:
Yuanhui SONG
1
;
Gnanbin SONG
Author Information
1. College of Bioengineering, Chongqing University, Chongqing 400044, China.
- Publication Type:Journal Article
- MeSH:
Cell Differentiation;
Cell Proliferation;
Humans;
Stem Cell Niche;
physiology;
Stem Cells;
cytology;
physiology
- From:
Journal of Biomedical Engineering
2009;26(1):195-198
- CountryChina
- Language:Chinese
-
Abstract:
Stem cells are a kind of specialized cell type with the ability of self-renewal and multilineage differentiation potential. They can proliferate and differentiate into many other cell types under a specific condition. However, proliferation and differentiation behaviors of stem cells depend on their located microenvironment, which is also named stem cell niche. An appropriate spatiotemporal dialog occurs between stem cells and niche to fulfill the balance of their self-renewal and differentiation. This review focused on several different stem cell niches and their relationship with proliferation and differentiation of stem cells.
